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GMP reductase : ウィキペディア英語版 | GMP reductase
GMP reductase (Guanosine 5'-monophosphate oxidoreductase ) is an enzyme that catalyses the irreversible and NADPH-dependent reductive deamination of GMP into IMP. NADPH + guanosine 5-phosphate = NADP+ + inosine 5-phosphate + NH3 It converts nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and maintains intracellular balance of A and G nucleotides. In melanocytic cells, GMP reductase gene expression may be regulated by MITF. ==See also==
* Purine metabolism
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